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5-HTP CR

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5-HTP CR has a delivery system that releases 5-HTP slowly and steadily over a period of time. 5-HTP is a drug-free amino acid derived from a plant that naturally increases the body’s level of serotonin, the chemical messenger that affects emotions, behavior, appetite, and sleep. Today’s stress-filled lifestyles and dietary practices may negatively affect how the body handles serotonin. Regular use of Unique Verve’s 5-HTP CR helps promote a more positive outlook and greater appetite control.*

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Description

Clinical Application:

  •  Supports Healthy Biosynthesis of Serotonin
  •  Supports Healthy Mood and Positive Outlook
  •  Supports Normal Appetite
  •  Supports Restful Sleep Pattern

Formulated To Exclude:

Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, and artificial preservatives.

Directions:

Take one tablet, up to two times daily, with a meal. Do not exceed recommended dose.
Consult your healthcare professional prior to use if you have, or suspect you have, a medical condition or are taking prescription drugs for depression, migraines, Parkinson’s disease, or psychiatric disorders. Not for use by children.

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)

Made and Packaged in the USA

Supplement Facts:

Serving Size 1 Tablet
Servings Per Container 60

Ingredients:

Calcium (as dicalcium phosphate dihydrate) 27 mg 2%
5-HTP (5-hydroxytryptophan) 100 mg ** (from Griffonia simplicifolia)(seed)

Other Ingredients:

Hydroxypropyl methylcellulose, hydroxypropyl cellulose, ascorbyl palmitate, silica, and coating (tapioca maltodextrin, sunflower lecithin, palm oil, and guar gum).

LEGAL DISCLAIMER:

*Disclaimer: Statements made regarding dietary supplements, or products sold through this website have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. You should consult with a healthcare provider before beginning any dietary supplements.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health concerns.

Discussion

5-hydroxytryptophan (5-HTP) is a precursor to serotonin. In the body, the essential amino acid tryptophan (when acted upon by the enzyme tryptophan hydroxylase) converts to 5-HTP. The compound is subsequently decarboxylated to serotonin, thereby elevating extracellular serum serotonin levels. Supplementing with 5-HTP bypasses the somewhat limiting conversion of tryptophan to 5-HTP. Oral 5-HTP is well-absorbed in the intestine without the need for a transporter; other amino acids do not compete with it for absorption. It easily crosses the blood-brain barrier, is not degraded by the enzymes that degrade tryptophan, and it is excreted through the kidneys.

Mood and Comfort: Serotonin regulates many normal brain activities, increases norepinephrine and dopamine, and is important in regulating mood and behavior. Adequate levels of serotonin are associated with normal calmness and relaxation.

Several studies have demonstrated that 5-HTP supports a healthy frame of mind, good energy levels, ease of movement, and restful sleep. Published studies (dose~100-600 mg/day) have also demonstrated the effectiveness of 5-HTP supplementation in supporting cerebral comfort.

Appetite: Used in a high dose (i.e., 300 mg/three times a day), 5-HTP decreased food consumption and reduced weight. This result may relate to the effect of 5-HTP in supporting normal hypothalamic regulation, which includes appetite homeostasis. However, nausea at this relatively high dose was a common complaint. In other research, sublingual 5-HTP administered five times per day for eight weeks in adult overweight women significantly supported feelings of post-meal hunger satisfaction.

Hormones and Sleep: 5-HTP is thought to effect the HPA axis, as it has the ability to raise plasma cortisol levels, to cause transient increase in growth hormone (at 150 mg dose), and in men only, to support healthy levels of thyroid stimulating hormone. Serotonin is also converted to melatonin; thus, supplementation has similar effects. Support of sleep quality is likely related to 5-HTP’s ability to increase the length of rapid eye movement (REM). In children, supplementation with 5-HTP may help modulate arousal level and support peaceful sleep.

REFERENCES

  1. Fibromyalgia and the serotonin pathway: https://pubmed.ncbi.nlm.nih.gov/9802912/  

  2. Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation: https://pubmed.ncbi.nlm.nih.gov/17176492/  

  3. 5-Hydroxytryptophan: a clinically-effective serotonin precursor: https://pubmed.ncbi.nlm.nih.gov/9727088/
  4. 5-hydroxytryptophan in major depression: a positron emission tomography study on patients and healthy volunteers: https://pubmed.ncbi.nlm.nih.gov/1882697/
  5. L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression: https://pubmed.ncbi.nlm.nih.gov/3265988/
  6. Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome: http://pubmed.ncbi.nlm.nih.gov/2193835/
  7. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study: https://pubmed.ncbi.nlm.nih.gov/1521674/
  8. L-5-hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo controlled study: https://headachejournal.onlinelibrary.wiley.com/doi/abs/10.1046/j.1526-4610.2000.00067.x
  9.  Plasma 5-hydroxytryptamine (5-HT) in migraine during an attack-free period: https://pubmed.ncbi.nlm.nih.gov/16643553/
  10. L-5-hydroxytryptophan can prevent nociceptive disorders in man: https://pubmed.ncbi.nlm.nih.gov/10721054/
  11. Disorder in the serotonergic system due to tryptophan hydroxylation impairment: a cause of hypothalamic syndrome? https://www.karger.com/Article/Abstract/271918
  12. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan: https://pubmed.ncbi.nlm.nih.gov/1384305/
  13. Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients: https://pubmed.ncbi.nlm.nih.gov/9705024/
  14. Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation: https://pubmed.ncbi.nlm.nih.gov/19752879/
  15. Inhibitory effect of ritanserin on the 5-hydroxytryptophan-mediated cortisol, ACTH and prolactin secretion in humans: https://pubmed.ncbi.nlm.nih.gov/1851310/
  16. Transient effect of L-5-hydroxytryptophan on pituitary function in men and women: https://pubmed.ncbi.nlm.nih.gov/6600170/
  17. Effects of 5-hydroxytryptophan on the sleep of normal human subjects: https://www.sciencedirect.com/science/article/abs/pii/0013469471901477
  18. L -5-hydroxytryptophan treatment of sleep terrors in children: https://pubmed.ncbi.nlm.nih.gov/15146330/

 

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    At my own will, I give a permission to request Natalie Maibenko, Unique Verve, Inc to order wellness test(s) through Vibrant America.

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    Nutritional, supplemental, fitness, and wellness information provided by the Functional Medicine Skincare Therapist, Natalie Maibenko, Unique Verve Inc is designed for educational purposes only. If the Client has any concerns or questions about her/his health, the Client should always consult with a physician or other healthcare professional. Do not disregard, avoid, or delay obtaining medical or health-related advice from the healthcare professional.

    Any claims made with respect to dietary supplements, including those made with respect to supplements available at Unique Verve, have not been evaluated by the Food and Drug Administration, and is not necessarily based on scientific evidence from any source. Dietary supplements are not intended to treat, diagnose, cure or prevent medical conditions or disease. You should consult with a healthcare provider before beginning any dietary supplement program.

    The Client understands that any therapies that the client undertakes at Unique Verve, Inc are undertaken of the client’s own free will. The Client accept that the ultimate responsibility for her/his health care is her/his own and that Functional Medicine Skincare Therapist, Natalie Maibenko, Unique Verve Inc is here to support the client in this. The client hereby agrees to assume full responsibility for any manner of loss, injury, claim or damage whatsoever, known or unknown, incurred as a result of same and the Client, her/his heirs, executors, administrators or assigns for any loss, injury, claim or damage sustained as a result of the Client’s attendance and/or participation.

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    5. I understand that due to the nature of the Detox and/or Skin Wellness program, it might involve cleansing reactions in the form of fatigue, headache, or other symptoms. These symptoms will abate with time. Because all individuals are unique, Unique Verve, Inc and a Functional Medicine Skincare Therapist, Natalie Maibenko can not gauge or guess client’s reaction(s) to the Detox and/or Skin Wellness program.
    6. DISCLAIMER and CONDITIONS: Functional Medicine and Skincare Therapist, Natalie Maibenko encourages the Client to continue to visit and to be treated by his/her healthcare professionals, including, without limitation, a physician. The client understands that Natalie Maibenko is not acting in the capacity of a doctor, licensed dietitian-nutritionist, therapist, psychologist or other licensed or registered professional. Accordingly, the client understands that the Functional Medicine and Skincare Therapist Natalie Maibenko is not providing health care, medical or nutrition therapy services and will not diagnose, treat or cure any disease, condition or other physical or mental ailment of the human body. Rather, Functional Medicine and Skincare  Therapist Natalie Maibenko serves as a coach, mentor and guide who helps a client to reach her/his own health and wellness goals through implementing incremental, positive, healthy, sustainable lifestyle changes that help the client to live and thrive using simple methods. The Client has chosen to work with the Functional Medicine and Skincare Therapist Natalie Maibenko and understands that the information received should not be seen as a medical or nursing advice and is not meant to take the place of the client seeing licensed health professionals. Nutritional, fitness, and wellness information provided by Functional Medicine and Skincare Therapist Natalie Maibenko, Unique Verve Inc is designed for educational purposes only. This information is not a substitute for, nor does it replace professional medical advice, diagnosis or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional. Do not disregard, avoid, or delay obtaining medical or health-related advice from your healthcare professional.
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    The Client acknowledges that the Client takes full responsibility for the Client’s life and well-being, as well as the lives and well-being of the Client’s family and children (where applicable), and all decisions made during and after this program. The Client expressly assumes the risks of the Program, whether or not such risks were created or exacerbated by the provider. The Client releases the Functional Medicine and Skincare Therapist Natalie Maibenko, his/her heirs, executors, administrators and assigns, its officers, directors, shareholders, employees, teachers, lecturers, agents, health counselors and staff (collectively, the Releases) from any and all liability, damages, causes of action, allegations, suits, sums of money, claims and demands whatsoever, in law, admiralty or equity, which against the Releases, the Client ever had, now has or will have in the future against the Releases, arising from the Client’s past or future participation in, or otherwise with respect to, the Program. Unique Verve, Inc and the Functional Medicine and Skincare Therapist, Natalie Maibenko is in no way liable for client’s health or safety.

    1. The Functional Medicine and Skincare Therapist, Natalie Maibenko, is not a licensed Dietitian, Naturopathic Doctor or Medical Physician or Doctor and does not diagnose diseases, disorders or conditions.
    2. Nutritional, fitness, and wellness information provided by the Functional Medicine and Skincare Therapist Natalie Maibenko, Unique Verve Inc is designed for educational purposes only. This information is not a substitute for, nor does it replace professional medical advice, diagnosis or treatment. If you have any concerns or questions about your health, you should always consult with a physician or other healthcare professional. Do not disregard, avoid, or delay obtaining medical or health-related advice from your healthcare professional.
    3. Any claims made with respect to dietary supplements, including those made with respect to supplements available at Unique Verve Inc by the Functional Medicine and Skincare Therapist Natalie Maibenko, have not been evaluated by the Food and Drug Administration, and is not necessarily based on scientific evidence from any source. Dietary supplements are not intended to treat, diagnose, cure or prevent medical conditions or disease. The client should consult with a healthcare provider before beginning any dietary supplement program.
    4. In providing wellness program to the client, the Functional Medicine and Skincare Therapist, Natalie Maibenko, is relying upon the truth, accuracy and completeness of all information the client have provided to her. Any recommendations the client follows for changes in diet, including the use of nutritional supplements, are entirely client’s responsibility.
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      The role of the program is to support and assist the client in reaching the goals, but the success depends primarily on the client’s own effort, motivation, dedication, desire commitment and follow-through.
      The Functional Medicine and Skincare Therapist, Natalie Maibenko does not guarantee that the client will attain a particular result, and the client understands that results differ by each individual. As with any health-related program or service, the results may vary, and will be based on many variables, including but not limited to, client’s individual capacity, life experience, unique health and genetic profile, starting point, expertise and level of commitment.
    6. The client understand that any therapies that she/he undertakes at Unique Verve, Inc are undertaken of her/his own free will.

    The client accepts that the ultimate responsibility for her/his health care is the client’s own and that the Functional Medicine and Skincare Therapist Natalie Maibenko, Unique Verve Inc is here to support the client in this.

    The client hereby agrees to assume full responsibility for any manner of loss, injury, claim or damage whatsoever, known or unknown, incurred as a result of same and the client, her/his heirs, executors, administrators or assigns for any loss, injury, claim or damage sustained as a result of the client’s attendance and/or participation.
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