5-HTP PLUS
$45.00 — or subscribe to save 5%
5-HTP Plus is a high potency, purity guaranteed, multi-ingredient formula. It includes pure 5-hydroxy tryptophan (5-HTP/activated tryptophan) as well as other supportive and highly bioavailable nutrients that have been shown to be helpful in enhancing the effectiveness of 5-HTP far beyond this ingredient taken by itself. 5-HTP Plus is as a chewable tablet so that it can be swallowed, chewed, or dissolved in the mouth. For those that have poor absorption or experience nausea from 5-HTP, or those that need quick effects, dissolving in the mouth is the optimal method of administration. This formula may help to lower the perception of stress, cut cravings, reduce appetite, support healthy mood, and enhance sleep (and thereby enhance healing and lower overall inflammation through better sleep), increasing calmness and optimizing stress tolerance and patience.*
Available on backorder
Description
5-HTP Plus Benefits:
- Â Supports Healthy Biosynthesis of Serotonin*
- Â Supports Healthy Mood and Positive Outlook*
- Â Supports Normal Appetite*
- Â Supports Restful Sleep Pattern*
Formulated To Exclude:
Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, and artificial preservatives.
5-HTP Plus Directions:
Suck on, chew, or swallow 1 tablet 1-3 times a day optimally at bedtime or as recommended by your practitioner.
Consult your healthcare professional prior to use if you have, or suspect you have, a medical condition or are taking prescription drugs for depression, migraines, Parkinson’s disease, or psychiatric disorders. Not for use by children.
QUALITY, PURITY, POTENCY GUARANTEED:
All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.
Manufactured in a US FDA inspected facility.
cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)
Purity and potency guaranteed! We use the highest quality raw materials available. Testing is done at various stages of production.
Supplement Facts:
Serving Size: 1 Chewable Vegetarian Tablet
Servings Per Container: 90 Chewable Tablets
5-HTP Plus Ingredients:
5HTP (5-hydroxytryptophane), Glycine, Vitamin B6, Pyridoxyl 5 Phosphate (P5P)
Other Ingredients:
Natural Proprietary Sweetener Blend (Dextrose, Stevia) Natural Flavors (Cherry,
Peppermint), Vegetarian Magnesium Stearate.
LEGAL DISCLAIMER
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. You should consult with a healthcare provider before beginning any dietary supplements.
Discussion
5-hydroxytryptophan (5-HTP) is a precursor to serotonin. In the body, the essential amino acid tryptophan (when acted upon by the enzyme tryptophan hydroxylase) converts to 5-HTP. The compound is subsequently decarboxylated to serotonin, thereby elevating extracellular serum serotonin levels. Supplementing with 5-HTP bypasses the somewhat limiting conversion of tryptophan to 5-HTP. Oral 5-HTP is well-absorbed in the intestine without the need for a transporter; other amino acids do not compete with it for absorption. It easily crosses the blood-brain barrier, is not degraded by the enzymes that degrade tryptophan, and it is excreted through the kidneys.
Mood and Comfort: Serotonin regulates many normal brain activities, increases norepinephrine and dopamine, and is important in regulating mood and behavior. Adequate levels of serotonin are associated with normal calmness and relaxation.
Several studies have demonstrated that 5-HTP supports a healthy frame of mind, good energy levels, ease of movement, and restful sleep. Published studies (dose~100-600 mg/day) have also demonstrated the effectiveness of 5-HTP supplementation in supporting cerebral comfort.
Appetite: Used in a high dose (i.e., 300 mg/three times a day), 5-HTP decreased food consumption and reduced weight. This result may relate to the effect of 5-HTP in supporting normal hypothalamic regulation, which includes appetite homeostasis. However, nausea at this relatively high dose was a common complaint. In other research, sublingual 5-HTP administered five times per day for eight weeks in adult overweight women significantly supported feelings of post-meal hunger satisfaction.
Hormones and Sleep: 5-HTP is thought to effect the HPA axis, as it has the ability to raise plasma cortisol levels, to cause transient increase in growth hormone (at 150 mg dose), and in men only, to support healthy levels of thyroid stimulating hormone. Serotonin is also converted to melatonin; thus, supplementation has similar effects. Support of sleep quality is likely related to 5-HTP’s ability to increase the length of rapid eye movement (REM). In children, supplementation with 5-HTP may help modulate arousal level and support peaceful sleep.
REFERENCES
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Fibromyalgia and the serotonin pathway: https://pubmed.ncbi.nlm.nih.gov/9802912/Â Â
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Tryptophan hydroxylase-2 gene variation influences personality traits and disorders related to emotional dysregulation:Â https://pubmed.ncbi.nlm.nih.gov/17176492/Â Â
- 5-Hydroxytryptophan: a clinically-effective serotonin precursor:Â https://pubmed.ncbi.nlm.nih.gov/9727088/
- 5-hydroxytryptophan in major depression: a positron emission tomography study on patients and healthy volunteers: https://pubmed.ncbi.nlm.nih.gov/1882697/
- L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression:Â https://pubmed.ncbi.nlm.nih.gov/3265988/
- Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome: http://pubmed.ncbi.nlm.nih.gov/2193835/
- Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study:Â https://pubmed.ncbi.nlm.nih.gov/1521674/
- L-5-hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo controlled study: https://headachejournal.onlinelibrary.wiley.com/doi/abs/10.1046/j.1526-4610.2000.00067.x
- Â Plasma 5-hydroxytryptamine (5-HT) in migraine during an attack-free period: https://pubmed.ncbi.nlm.nih.gov/16643553/
- L-5-hydroxytryptophan can prevent nociceptive disorders in man: https://pubmed.ncbi.nlm.nih.gov/10721054/
- Disorder in the serotonergic system due to tryptophan hydroxylation impairment: a cause of hypothalamic syndrome? https://www.karger.com/Article/Abstract/271918
- Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan: https://pubmed.ncbi.nlm.nih.gov/1384305/
- Effects of oral 5-hydroxy-tryptophan on energy intake and macronutrient selection in non-insulin dependent diabetic patients: https://pubmed.ncbi.nlm.nih.gov/9705024/
- Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation: https://pubmed.ncbi.nlm.nih.gov/19752879/
- Inhibitory effect of ritanserin on the 5-hydroxytryptophan-mediated cortisol, ACTH and prolactin secretion in humans: https://pubmed.ncbi.nlm.nih.gov/1851310/
- Transient effect of L-5-hydroxytryptophan on pituitary function in men and women: https://pubmed.ncbi.nlm.nih.gov/6600170/
- Effects of 5-hydroxytryptophan on the sleep of normal human subjects: https://www.sciencedirect.com/science/article/abs/pii/0013469471901477
- L -5-hydroxytryptophan treatment of sleep terrors in children: https://pubmed.ncbi.nlm.nih.gov/15146330/
Why Buy From Us
- PHARMACEUTICAL GRADE
- we offer highest quality supplements that are based on scientifically researched ingredients that are bioavailable and bioactive
- our formulas are made and packaged to order in USA, thus you’re getting always the freshest product
- manufactured in the temperature and humidity regulated facility
- we store our supplements in the temperature and humidity regulated facility, thus maintaining potency and freshness of active ingredients. Unlike many supplements on the market that are not. Amazon for instance came out with the statement saying they can’t control counterfeits in the supplements, let alone storage conditions.
- our formulas are free of fillers and binders
- our formulas DO NOT CONTAIN: wheat, gluten, soy, animal or dairy products, fish (unless it’s an Omega 3 supplement), shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organism (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
- manufactured in USA in a GMP compliant facility
- ingredients tested for purity, quality, potency, and composition
- best manufacturers from all over the USA
HOW TO DETERMINE THE QUALITY OF SUPPLEMENTS?
An important part of any supplement plan is choosing high-quality products. This guarantees that the vitamins, minerals, herbs, botanicals and other nutrients you take will provide the benefits your body needs. To be considered a supplement must be tested by an outside (third-party) source that can verify its quality.
NUTRITIONAL SUPPLEMENTS ARE DIVIDED INTO FOUR CATEGORIES:
- Pharmaceutical Grade – supplements of this grade meet the highest regulatory requirements for purity, dissolution and absorption as verified by an outside party. These supplements must be 99% pure, with no binders, fillers, dyes, or other unknown substances. These are the supplements that are most often sold by licensed healthcare practitioners. Unique Verve Supplements are Pharmaceutical Grade!
- Medical Grade – these supplements are of a high grade although they may not conform to the standards of pharmaceutical grade supplements.
- Cosmetic or nutritional grade – these supplements are most often sold in the health food stores and are not tested for purity, dissolution or absorption. They may not have a high concentration of listed active ingredients.
- Feed or agricultural grade – these supplements are used for the veterinary purposes. Never use supplements of this grade.
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MARTHA MILLER (verified owner) –