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MemorOpti is a unique combination of nutrients and botanicals that support cognitive function and a healthy memory. It features select B vitamins, including Quatrefolic®, a patented form of 5-MTHF; the herbs Ginkgo Biloba and Bacopa Monnieri; nutrients that provide antioxidant activity; and brain-specific nutrients such as acetyl-L-carnitine and sunflower-derived phosphatidylserine. This comprehensive formula addresses the multiple pathways involved in neurological health by supporting oxidant and cytokine balance, methylation, mitochondrial function, and endocrine balance.*

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Clinical Application:

  • Helps Support Normal, Healthy Cognitive Function*
  • May Support the Health of Brain Tissue*

Formulated To Exclude:

Wheat, gluten, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.


Take one capsule twice daily, or as directed by your healthcare professional.
Consult your healthcare professional prior to use. Individuals taking medication should discuss potential interactions with their healthcare professional.

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)

Made and Packaged in the USA

Supplement Facts:

Serving Size: 1 Capsules
Servings Per Container: 60


Vitamin B6 (as pyridoxal 5’-phosphate) 5 mg 294%

Folate (as (6S)-5-methyltetrahydrofolic acid, glucosamine salt)S1 170 mcg DFE 43%

Vitamin B12 (as methylcobalamin) 100 mcg 4,167%

Acetyl-L-Carnitine (as acetyl-L-carnitine HCL) 250 mg **

N-Acetyl-L-Cysteine 100 mg **

Ginkgo Extract (Ginkgo biloba) (leaf) (20% ginkgoflavonglycosides and 5% terpene lactones) 60 mg **

Bacopa Extract (Bacopa monnieri) (whole plant) (8% bacosides) 50 mg **

PhospatidylserineS2  15 mg **

Trans-Resveratrol (from Polygonum cuspidatum root extract) 1 mg **

Huperzine A (from Huperzia serrata) (whole plant) 100 mcg **

** Daily Value not established.


Other Ingredients:

Capsule (hypromellose), stearic acid, calcium silicate, tricalcium phosphate, silica, magnesium stearate, and microcrystalline cellulose.


*Disclaimer: Statements made, or products sold through this website have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health concerns.

You should consult with a healthcare provider before beginning any dietary supplement program.


Vitamins B6 (as pyridoxal 5’-phosphate), B12 (as methylcobalamin), and folate (as 5-MTHF) are essential homocysteine remethylation cofactors; as such, they support the maintenance of healthy homocysteine levels. Normal blood levels of homocysteine are associated with healthy cognition in the elderly and healthy cerebrovascular function. [1] The brain may be protected by improving methylation by providing the nutritional cofactors needed for proper functioning of the methionine cycle. *[2]

5-MTHF (5-methyltetrahydrofolate) may better support folate nutrition in those with digestive issues and those with genetic variations in folic acid metabolism. The form of 5-MTHF in MemorOpti is Quatrefolic, which is proven to have greater stability, solubility, and bioavailability over calcium salt forms of 5-MTHF.*

N-Acetylcholine-Cysteine is capable of crossing the blood-brain barrier and is known to combat oxidative stress, and reduced oxidative stress may support healthier nerve tissue. [3]

L-carnitine is a vital cofactor for mitochondrial oxidation of fatty acids providing the brain with an energy substrate. Acetylcholine-L-carnitine, an ester of L-carnitine, possesses properties that may be effective in supporting healthy cognition with age.* [4,5]

The phospholipid phosphatidylserine (PS) plays an important functional role in membrane-related processes in the brain and regulates the release of acetylcholine, dopamine, and noradrenaline. PS appears to support neuronal health and healthy brain function, possibly through its effect on cytokine production and their influence on microglia.*[6]

Gingko Biloba leaf extract contains two main bioactive constituents – ginkgoflavonglycosides (24%) and terpene lactones (6%) – and is used in the formula because of its reported stress-alleviating and memory-supportive effects as well as its ability to support the health and integrity of neurons. The mechanisms of action may be mediated through its antioxidant, antihypoxic, and micro circulatory actions.*[7]

The Ayurvedic herb Bacopa Monniera has reported cognition-facilitating, cytokine-modulating, and anti-stress effects. These effects are thought to be mediated through its remarkable free-radical scavenging capacity and its protective effect of DNA cleavage.*[8]

Vinpocetine is derived from vincamine, an alkaloid extracted from the periwinkle plant (Vinca minor). It has been used extensively in Eastern Europe, and more recently in the United States, to support cerebrovascular health and healthy mental function. Vinpocetine’s roles in supporting brain function are multi-modal and include its influence on cerebral circulation, its antioxidant activity in the brain, and its rol in affecting ion channels and cytokine production.* [9-11] Together, these varied actions support overall brain tissue health and function. The efficacy and safety of vinpocetine have been tested and validated by in vitro, animal, and human studies. Many human studies demonstrate positive results in neurological functioning – primarily related to capillary blood flow and cellular metabolism.*[12-15]

Huperzine A (HupA), like vinpocetine, affects ion channels. Such activity has been found to support healthy learning and memory. HupA may have a positive effect on levels of acetylcholine through its action on acetylcholinesterase (AChE). Acetylcholine is one of the chemicals that our nerves use to communicate in the brain, muscles, and other areas. HupA has been found to support healthy cognition in a broad range of animal models, and phase IV clinical trials in China demonstrated that HupA was valuable in promoting healthy recall and cognition in elderly subjects.*[16]


  1. Malouf R, Grimley Evans J. The effect of vitamin B6 on cognition:
  2. Miller AL. The methionine-homocysteine cycle and its effects on cognitive diseases:
  3. Farr SA, Poon HF, Dogrukol-Ak D, et al. The antioxidants alpha-lipoic acid and N-acetylcysteine reverse memory impairment and brain oxidative stress in aged SAMP8 mice:
  4. Virmani A, Binienda Z. Role of carnitine esters in brain neuropathology:
  5. Milgram NW, Araujo JA, Hagen TM, et al. Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests:
  6. Hashioka S, Han YH, Fujii S, et al. Phosphatidylserine and phosphatidylcholine- containing liposomes inhibit amyloid beta and interferon-gamma-induced microglial activation:
  7. Mahadevan S, Park Y. Multifaceted therapeutic benefits of Ginkgo biloba L.: chemistry, efficacy, safety, and uses:
  8. Russo A, Izzo AA, Borrelli F, et al. Free radical scavenging capacity and protective effect of Bacopa monniera L. on DNA damage:
  9. Hadjiev D. Asymptomatic ischemic cerebrovascular disorders and neuroprotection with vinpocetine:
  10. Muravyov AV, Yakusevich VV, Chuchkanov FA, et al. Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study:
  11. Vinpocetine. Monograph:
  12. Valikovics A. Investigation of the effect of vinpocetine on cerebral blood flow and cognitive functions [in Hungarian]:
  13. Chukanova EI. Efficacy of cavinton in the treatment of patients with chronic blood flow insufficiency. Russian multicenter clinical- epidemiological program “CALIPSO” [in Russian]:
  14. Chukanova EI. Cavinton in the complex treatment of patients with chronic cerebrovascular insufficiency [in Russian]:
  15. Bagoly E, Fehér G, Szapáry L. The role of vinpocetine in the treatment of cerebrovascular diseases based in human studies [in Hungarian]:
  16. Wang R, Yan H, Tang XC. Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine:


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