PhosphaCholine

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PhosphaCholine provides a concentrated phospholipid complex — phosphatidylcholine (PC), phosphatidylinositol (PI), and phosphatidylethanolamine (PE) — from a soy lecithin source. Phosphatidylcholine is the most abundant phospholipid in human cell membranes and the primary dietary source of choline — an essential nutrient foundational to neurological function, liver health, healthy cholesterol metabolism, and the structural integrity of every cell in the body.* 100 softgels. Contains soy.

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Unique Verve’s PhosphaCholine Key Benefits & Actions

  • Provides phosphatidylcholine — the most abundant phospholipid in human cell membranes and primary dietary choline source*
  • Supports healthy cholesterol metabolism through phosphatidylcholine’s role in lipid transport and bile composition*
  • Supports healthy liver function — phosphatidylcholine is a critical structural component of hepatocyte cell membranes and supports healthy lipid processing in the liver*
  • Supports healthy neurological function and neuronal membrane integrity through phosphatidylcholine’s role in myelin sheath structure*
  • Supports healthy acetylcholine synthesis — phosphatidylcholine is the primary precursor to the neurotransmitter acetylcholine*
  • Supports healthy mood and cognitive function through choline’s role in neurotransmitter and cell-signaling pathways*
    Phosphatidylinositol supports healthy cell-signaling pathways including inositol phospholipid second messenger activity*
  • Supports healthy skin cell membrane integrity and GI mucosal cell membrane structure*

Unique Verve’s PhosphaCholine delivers a concentrated phospholipid complex — phosphatidylcholine (PC), phosphatidylinositol (PI), and phosphatidylethanolamine (PE) — from a purified soy lecithin source. These three phospholipids are the primary structural components of cell membranes throughout the human body, and their combined supplementation provides broad-spectrum support for cell membrane integrity, neurological function, liver health, and lipid metabolism.*

Phosphatidylcholine

The Body’s Primary Phospholipid Phosphatidylcholine is the most abundant phospholipid in human cell membranes — comprising approximately 40–50% of the phospholipid content of the plasma membrane in most cell types. It forms the foundational bilayer structure of cell membranes, governing membrane fluidity, receptor function, and the selective permeability that allows cells to maintain their internal environment while interacting with surrounding tissue.*

Phosphatidylcholine is also the body’s primary dietary source of choline — an essential nutrient that the body cannot produce in sufficient quantities without dietary or supplemental supply. Choline serves as the precursor to acetylcholine (the neurotransmitter foundational to learning, memory, and cognitive processing), as a methyl donor in the methylation cycle (supporting healthy homocysteine metabolism), and as a structural component of cell membranes throughout the body.*

Liver Health and Lipid Metabolism

The liver has an exceptionally high phosphatidylcholine requirement — both for the structural integrity of hepatocyte cell membranes and for the assembly and secretion of VLDL (very low-density lipoprotein) particles, which are the liver’s primary vehicle for exporting lipids from the liver into circulation. Adequate phosphatidylcholine availability supports healthy hepatic lipid processing and healthy lipid transport.*

Phosphatidylcholine also plays a direct role in bile composition — it is a primary component of bile micelles alongside bile acids and cholesterol. This role supports healthy cholesterol metabolism through the biliary route and contributes to healthy fat digestion and absorption.*

Neurological Function and Mood Support

The nervous system is among the most phospholipid-rich systems in the body — neuronal cell membranes and myelin sheaths (the protective coating of nerve fibers) are composed primarily of phospholipids including phosphatidylcholine, phosphatidylethanolamine, and sphingomyelin. Maintaining the structural integrity of neuronal membranes supports healthy nerve conduction, synaptic function, and neuroplasticity.*

Phosphatidylcholine’s role as a choline precursor is particularly relevant to neurological health — as the rate-limiting substrate for acetylcholine synthesis in cholinergic neurons. Acetylcholine is the primary neurotransmitter of the parasympathetic nervous system and is foundational to learning, memory, and healthy cognitive function. Choline’s role as a methyl donor also supports healthy mood through its contribution to neurotransmitter methylation pathways.*

Phosphatidylinositol and Cell Signaling

Phosphatidylinositol (PI) and its phosphorylated derivatives — phosphoinositides — serve as critical second messengers in multiple intracellular signaling cascades, including those triggered by growth factors, hormones, and neurotransmitters. PI contributes to healthy cellular communication and signal transduction throughout the body.*

Phosphatidylethanolamine and Membrane Function

Phosphatidylethanolamine (PE) is the second most abundant phospholipid in mammalian cell membranes. It is particularly enriched in the inner leaflet of the plasma membrane and in mitochondrial membranes, where it supports healthy mitochondrial function and membrane dynamics. PE also serves as a substrate for the synthesis of phosphatidylcholine through the PEMT (phosphatidylethanolamine N-methyltransferase) pathway in the liver.*

Does Not Contain

Wheat, gluten, animal or dairy products, fish, shellfish, artificial colors, artificial sweeteners, or artificial preservatives.

Warning: Contains soy.

Directions

Dosage Instructions for PhosphaCholine supplement:

Adults: As a dietary supplement take 1 Soft Gel a day or as directed by your health care practitioner.

Quality, purity, potency guaranteed:

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)

Purity and Potency Guaranteed! We use the highest quality raw materials available. Testing is done at various stages of production.

Made and Packaged in the USA

Supplement Facts & Ingredients

Serving Size: 1 soft gel
Servings Per Container: 100

Lecithin, Phosphatidyl choline, phosphatidyl inositol, Phosphatidyl ethanolamine

Other Ingredients:

Gelatin (bovine), glycerin, and purified water.

ALLERGEN WARNING: CONTAINS SOY.

**Activity level at time of manufacture

Legal disclaimer

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner.

REFERENCES

  1. The effect of dietary phosphatidylcholine supplementation on lipid profile in mild hyperlipidaemic individuals
  2. Phosphatidylcholine restores neuronal plasticity of neural stem cells under inflammatory stress

  3. Beneficial effect of phosphatidylcholine supplementation in alleviation of hypomania and insomnia in a Chinese bipolar hypomanic boy and a possible explanation to the effect at the genetic level

  4. Choline in anxiety and depression: the Hordaland Health Study

  5. Regression of Liver Steatosis Following Phosphatidylcholine Administration: A Review of Molecular and Metabolic Pathways Involved

Why Buy From Us

  • PHARMACEUTICAL GRADE
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  • our formulas are made and packaged to order in USA, thus you’re getting always the freshest product
  • manufactured in the temperature and humidity regulated facility
  • we store our supplements in the temperature and humidity regulated facility, thus maintaining potency and freshness of active ingredients. Unlike many supplements on the market that are not. Amazon for instance came out with the statement saying they can’t control counterfeits in the supplements, let alone storage conditions.
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  • our formulas DO NOT CONTAIN: wheat, gluten, soy, animal or dairy products, fish (unless it’s an Omega 3 supplement), shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organism (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.
  • manufactured in USA in a GMP compliant facility
  • ingredients tested for purity, quality, potency, and composition
  • best manufacturers from all over the USA

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