Tri-Peptide Complex Avance Elixir

Environ Tri-Peptide Complex Avance Elixir – A serum built around the most evidence-supported peptide systems in skincare

The Tri-Peptide Complex Avance Elixir is Environ’s most comprehensive standalone peptide serum — a multi-mechanism formula that addresses collagen synthesis, collagen protection, structural protein quality, and skin tone evenness simultaneously. Understanding why each peptide component was selected requires briefly understanding how the extracellular matrix (ECM) changes over time.

The ECM — the structural scaffold of the dermis — is primarily composed of collagen (I, III, and IV), elastin, fibronectin, and glycosaminoglycans including hyaluronic acid. With time and UV exposure, two processes accelerate its degradation: fibroblasts produce less structural protein, and matrix metalloproteinases (MMPs) — enzymes activated by UV and inflammatory stress — break down existing collagen at an increasing rate. The Avance Elixir’s peptide system targets both sides of this equation.

The peptide complex in the Tri-Peptide Complex Avance Elixir

Palmitoyl Tripeptide-38 (Matrixyl Synthe’6®): The most advanced of the Matrixyl peptide series, Tripeptide-38 is a messenger peptide that signals fibroblasts to synthesize six structural proteins simultaneously: collagen I, III, and IV; fibronectin; hyaluronic acid; and laminin-5. This makes it a genuinely comprehensive structural support agent rather than a collagen-only stimulator. Clinical studies on Matrixyl Synthe’6® have documented meaningful improvements in skin surface texture and structural quality after regular use.

Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 (Matrixyl 3000®): The original, well-researched Matrixyl complex. Tripeptide-1 mimics a collagen breakdown fragment that signals fibroblasts to produce more collagen — a feedback signaling mechanism the skin uses naturally. Tetrapeptide-7 inhibits the IL-6 signaling pathway that activates MMPs — supporting the rate at which existing collagen is maintained. Together these produce a dual effect: more collagen synthesized and existing collagen better preserved.

Tripeptide-10 Citrulline: A peptide with specific activity on fibrillin — the protein component of elastic microfibrils that maintain the elasticity and resilience of the skin’s structural network. As fibrillin changes over time, skin loses its ability to snap back after expression and movement. Tripeptide-10 Citrulline addresses this fibrillin dimension that collagen-targeted peptides alone cannot reach.

Tripeptide-1 (Copper Tripeptide GHK-Cu precursor): Supports fibroblast activation and healthy skin repair processes.

Reproage™ (Astragalus, Atractylodes, and Bupleurum Root Extracts): An adaptogenic botanical complex supporting the skin’s gene expression pathways and stress-resistance mechanisms.

Pseudoalteromonas Ferment Extract: A marine-derived fermentation extract with excellent moisturizing properties and documented ability to support dermal collagen integrity against environmental stress.

Hydrolyzed Wheat Protein and Hydrolyzed Soy Protein: Plant-derived proteins that form a temporary surface film on the skin, providing an immediate firming visual effect while the deeper peptide work progresses over time.

Where does the Tri-Peptide Complex Avance Elixir fit in the Environ system

The Avance Elixir is compatible with any stage of the AVST Step-Up System and adds a comprehensive collagen and structural peptide layer to the routine. It works especially effectively when used before cosmetic needling, which temporarily increases the permeability of the stratum corneum and enhances the depth of active ingredient delivery.

At Unique Verve, advanced peptide protocols are typically recommended alongside a functional medicine assessment — recognizing that skin structural health reflects both topical and internal nutritional factors. Our VIP Functional Medicine Program integrates topical protocols with comprehensive internal assessment for a complete approach to skin health.

How to use

After cleansing and toning (and cosmetic needling for advanced users), apply the Avance Elixir and massage gently into the face and neck before your AVST vitamin A moisturiser. Use morning and/or evening. The Elixir may be used alongside the Avance Moisturiser, or independently of it, depending on your skin’s needs and your practitioner’s recommendations.

Contains: Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein.

Ingredients

Aqua (Water), Glycerin, Butylene Glycol, Xanthan Gum, Astragalus Membranaceus Root Extract, Atractyloides Macrocephala Root Extract, Bupleurum Falcatum Root Extract, Polysorbate 20, Palmitoyl Tetrapeptide-7, Pseudoalteromonas Ferment Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Tripeptide-10 Citrulline, Palmitoyl Tripeptide-1, Lecithin, Hydroxypropyl Cyclodextrin, Palmitoyl Tripeptide-38, Sodium Lactate, Carbomer, Tripeptide-1, Caprylyl Glycol, Phenoxyethanol, Disodium EDTA, Triethanolamine.

Unique Verve is an authorized Environ stockist. Environ products are only available through authorized professionals — purchasing through an authorized retailer ensures product authenticity and proper storage.