Hydro-Lipidic 3DSynerge Filler Creme

Environ Hydro-Lipidic 3DSynerge Filler Creme – Addressing the volume dimension of skin ageing

Most topical anti-ageing strategies address what happens at the surface: cell turnover, collagen synthesis, antioxidant protection. But the visible “deflation” of ageing skin — the hollowing of cheeks, the deepening of nasolabial folds, the loose, unsupported look of skin that has lost its internal scaffolding — is driven by a different mechanism: the progressive decline of both hyaluronic acid in the dermis and adipose (fat) volume in the deeper tissue layers. This dimension of ageing is what injectable fillers address. The Hydro-Lipidic 3DSynerge Filler Creme is formulated to target the same loss at the topical level, through a combination of four distinct active systems.

The four active systems within the Hydro-Lipidic 3DSynerge Filler Creme

HyaCare® (Hydrolyzed Hyaluronic Acid) + OtimHyal™: HyaCare is a low-molecular-weight hydrolyzed HA that penetrates more effectively into the stratum corneum than standard high-molecular-weight HA, providing dermal hydration rather than just surface moisturization. OtimHyal™ is a patented HA-derivative that signals hyaluronan synthase activity — the enzyme responsible for endogenous HA production — effectively prompting the skin to produce more of its own hyaluronic acid over time. Together they address both immediate hydration and the longer-term restoration of the skin’s HA matrix.

Adifyline® (Acetyl Hexapeptide-38): A patented adipogenic (fat-cell-stimulating) peptide that mimics the growth factor PDGF-BB, which is involved in adipocyte differentiation. In the context of facial skin, this means it targets the loss of subcutaneous fat volume that contributes to the sunken, deflated appearance of ageing skin — a mechanism that is genuinely distinct from collagen-targeting or HA-filling approaches.

Reproage™ (Astragalus, Atractylodes, and Bupleurum Root Extracts): A complex of three traditional botanical root extracts that, in combination, have been shown to activate pathways associated with skin’s youthful properties — specifically genes involved in the extracellular matrix and skin’s resistance to ageing stressors. Environ uses this same complex in the Tri-Peptide Complex Avance products.

Meritage™ (Antioxidant Complex): A proprietary antioxidant system providing protection against future oxidative damage — preventing the ongoing breakdown of the collagen and HA matrix that the formula’s other actives are working to restore.

Acetyl Hexapeptide-8 (Argireline): The same neuromuscular peptide found in the Frown Serum, contributing an expression-line softening effect to complement the volumizing actions above.

Hydro-Lipidic 3DSynerge Filler Creme pairing and protocol notes

The 3DSynerge Filler Creme is for those experiencing visible facial volume loss — the deflation and hollowing that becomes pronounced from the mid-40s onwards, and is accelerated by both chronological ageing and hormonal decline (estrogen plays a significant role in maintaining dermal HA and subcutaneous fat). It is most impactful for those at AVST steps 3–5 or using one of the Environ’s C-Quence Vitamin A serums or the Tri-Retinoid Serums, where the skin’s vitamin A loading is sufficient to support the optimal cell response to the formula’s active ingredients. It can be introduced at any step of the vitamin A system.

How to use

After cleansing and toning, and ideally after cosmetic needling for advanced users, apply to the face and neck and massage gently before applying your AVST vitamin A moisturiser. Use morning and evening. This product may be used alongside the Tri-Peptide Complex Avance Elixir or Moisturiser as part of an advanced anti-ageing protocol.

Ingredients

Aqua (Water), Cetearyl Alcohol, Glycerin, Butylene Glycol, Hydrolyzed Yeast Extract, C12-15 Alkyl Benzoate, Glyceryl Stearate, Hydrogenated Olive Oil, Sodium Citrate, Cetearyl Ethylhexanoate, Dimethicone, Ethylhexyl Methoxycinnamate, PEG-40 Hydrogenated Castor Oil, PEG-40 Stearate, Simmondsia Chinensis (Jojoba) Seed Oil, Olea Europaea (Olive) Fruit Oil, Olea Europaea (Olive) Oil Unsaponi ables, Acetyl Hexapeptide-38, Acetyl Hexapeptide-8, Astragalus Membranaceus Root Extract, Atractylodes Macrocephala Root Extract, Bupleurum Falcatum Root Extract, Hydrolyzed Hyaluronic Acid, Lecithin, Isopropyl Myristate, Ceteareth-20, Tocopherol, Xanthan Gum, Cetyl Hydroxyethylcellulose, Disodium EDTA, Disodium Phosphate, Citric Acid, Sodium Phosphate, BHT, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Polyglucuronic Acid, Parfum (Fragrance), Benzyl Salicylate, Hexyl Cinnamal, Limonene,

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