Berberine Herbal Complex

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This formula provides concentrated extracts of Barberry (Berberis vulgaris), Oregon Grape (Berberis aquifolium), and Goldenseal (Hydrastis canadensis) in a very high potency formula. These herbs are believed to help maintain a healthy intestinal tract and support a healthy balance of gut bacteria. They also have immune supporting and insulin sensitivity improving benefits.

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Key Benefits & Actions:

  • Improves Insulin Sensitivity and Secretion
  • Improves Glucose Metabolism
  • Anti-Diabetic Potential
  • Inhibits Inflammation
  • Supports Healthy Gut Microbiome
  • Antifungal/ Anti-Candida
  • Anti-SIBO

Does Not Contain:

Wheat, gluten, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.



Dosage Instructions: Take 1-2 capsules 1-3 times a day or as directed by your healthcare practitioner.

Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner.

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)

Purity and Potency Guaranteed! We use the highest quality raw materials available. Testing is done at various stages of production.

Made and Packaged in the USA

Supplement Facts:

Serving Size: 2 vegetarian capsules
Servings Per Container: 45


Barberry (berberis vulgaris), oregon grape (berberis aquifolium), goldensea (hydrastis canadensis)

Other Ingredients:

Vegetarian capsule (Hypromellose, Purified Water), Rice Flour.


*Disclaimer: Statements made regarding dietary supplements, or products sold through this website have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease.Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner.


Improves Insulin Sensitivity & Secretion (1, 2, 3)

Biochemical studies have shown that berberine improve insulin sensitivity and insulin secretion.

Induces Glucose Metabolism and Inhibits Inflammation (1, 2, 3) 

Berberine induces glucose metabolism by activating AMPK signaling and inhibition of inflammation.

Potentially Anti-Diabetic (1, 2, 3)

Metabolic syndrome is a group of clinical syndromes determined by heredity, environment, living habits and other factors, whose main mechanism is insulin resistance. Patients have symptoms including central obesity, atherosclerosis, rise of blood lipid, pathoglycemia and elevation of blood pressure, which may be accompanied by microalbuminuria, hyperuricemia and long-term rise of chronic inflammatory cytokines.  Berberine can regulate various metabolic disorders of metabolic syndrome, which has advantages of wide medicinal herbs resources, low price, smaller adverse reactions, and is also safe and convenient.

Supports Healthy Gut Microbiota (3, 4)

Berberine has potential value in the treatment of liver diseases by reshaping the structure of the gut microbiota, especially by modulating the abundance of SCFA-producing bacteria (for example, Clostridium and Bacillus) and Akkermansia muciniphila.

Berberine has also been shown to enrich the population of butyrate-producing bacteria in the Gut Microbiota, thus promoting the synthesis of butyrate via the acetyl CoA-butyryl CoA-butyrate pathway. Subsequently, the butyrate enters the blood and reduces the levels of lipids and glucose

May be therapeutic against various types of chronic diseases (3, 4)

Berberine may be therapeutic against various types of chronic diseases, such as obesity, DM, inflammatory bowel disease (IBD), atherosclerosis, Alzheimer’s disease, rheumatoid arthritis, and cardiovascular diseases, due to its multiple-target effects.

Antifungal, Anti-Candida (5)

Berberine exhibited significant antifungal activity in Candida spp. The results provide a useful reference for multiple Candida infections and biofilm infections associated with antifungal resistance. Therefore, berberine might have novel therapeutic potential as an antifungal agent or a major active component of antifungal drugs.

Anti-SIBO (6)

Berberine effects to the gut may provide therapeutic targets for SIBO. Herbal therapy containing berberine is equivalent to rifaximin for the resolution of SIBO.



  1. Addressing the preventive and therapeutic perspective of berberine against diabetes:,signaling%20and%20inhibition%20of%20inflammation.

  2. Effects of berberine on glucose-lipid metabolism, inflammatory factors and insulin resistance in patients with metabolic syndrome:

  3. Berberine influences multiple diseases by modifying gut microbiota:,and%20Bacillus)%20and%20Akkermansia%20muciniphila.
  4. Effects of Berberine on the Gastrointestinal Microbiota:

  5. In vitro Antifungal Effects of Berberine Against Candida spp. In Planktonic and Biofilm Conditions:,infections%20associated%20with%20antifungal%20resistance.

  6. Berberine and rifaximin effects on small intestinal bacterial overgrowth: Study protocol for an investigator-initiated, double-arm, open-label, randomized clinical trial (BRIEF-SIBO study):,single%20agent%20in%20SIBO%20patients.


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