Berberine Herbal Complex

Discussion

Improves Insulin Sensitivity & Secretion (1, 2, 3)

Biochemical studies have shown that berberine improve insulin sensitivity and insulin secretion.

Induces Glucose Metabolism and Inhibits Inflammation (1, 2, 3) 

Berberine induces glucose metabolism by activating AMPK signaling and inhibition of inflammation.

Potentially Anti-Diabetic (1, 2, 3)

Metabolic syndrome is a group of clinical syndromes determined by heredity, environment, living habits and other factors, whose main mechanism is insulin resistance. Patients have symptoms including central obesity, atherosclerosis, rise of blood lipid, pathoglycemia and elevation of blood pressure, which may be accompanied by microalbuminuria, hyperuricemia and long-term rise of chronic inflammatory cytokines.  Berberine can regulate various metabolic disorders of metabolic syndrome, which has advantages of wide medicinal herbs resources, low price, smaller adverse reactions, and is also safe and convenient.

Supports Healthy Gut Microbiota (3, 4)

Berberine has potential value in the treatment of liver diseases by reshaping the structure of the gut microbiota, especially by modulating the abundance of SCFA-producing bacteria (for example, Clostridium and Bacillus) and Akkermansia muciniphila.

Berberine has also been shown to enrich the population of butyrate-producing bacteria in the Gut Microbiota, thus promoting the synthesis of butyrate via the acetyl CoA-butyryl CoA-butyrate pathway. Subsequently, the butyrate enters the blood and reduces the levels of lipids and glucose

May be therapeutic against various types of chronic diseases (3, 4)

Berberine may be therapeutic against various types of chronic diseases, such as obesity, DM, inflammatory bowel disease (IBD), atherosclerosis, Alzheimer’s disease, rheumatoid arthritis, and cardiovascular diseases, due to its multiple-target effects.

Antifungal, Anti-Candida (5)

Berberine exhibited significant antifungal activity in Candida spp. The results provide a useful reference for multiple Candida infections and biofilm infections associated with antifungal resistance. Therefore, berberine might have novel therapeutic potential as an antifungal agent or a major active component of antifungal drugs.

Anti-SIBO (6)

Berberine effects to the gut may provide therapeutic targets for SIBO. Herbal therapy containing berberine is equivalent to rifaximin for the resolution of SIBO.