B-Complex

Unique Verve’s B-Complex – What Makes It Different

• Provides all eight B vitamins in activated, methylated, or coenzyme forms for direct cellular use*
• Quatrefolic® delivers folate as (6S)-5-MTHF — the most bioavailable form, bypassing MTHFR conversion*
• MecobalActive™ methylcobalamin provides B12 in its neurologically active form for immediate cellular use*
• Benfotiamine — a fat-soluble, highly bioactive form of thiamine — supports carbohydrate metabolism and healthy nerve function*
• Supports healthy methylation cycle function — critical for DNA synthesis, detoxification, and gene expression*
• Supports healthy cardiovascular function through homocysteine metabolism*
• Supports adrenal function, healthy nervous system function, and sustained energy metabolism*
• Supports healthy mood, mental function, and cognitive performance*

Unique Verve’s B-Complex is a full-spectrum B vitamin formula built around a single principle: bioavailability first.

Every B vitamin in this formula is provided in the activated, methylated, or most physiologically usable form available — not the cheapest synthetic form that requires additional conversion steps the body may not efficiently perform.

Why Form Matters

The majority of B-complex supplements on the market use synthetic, non-activated forms: cyanocobalamin instead of methylcobalamin, folic acid instead of methylfolate, pyridoxine HCl instead of P5P, riboflavin instead of riboflavin-5-phosphate. Each of these requires enzymatic conversion in the body before it can be utilized. These conversions are enzyme-dependent, and for a significant portion of the population — particularly those with MTHFR gene variants — the conversion is incomplete or inefficient. This formula bypasses that problem entirely by delivering the active end-forms directly.

Quatrefolic® (Folate as (6S)-5-Methyltetrahydrofolic Acid) Quatrefolic® is a patented, glucosamine salt form of 5-MTHF — the biologically active form of folate that the body actually uses. Unlike folic acid, which requires a four-step enzymatic conversion process (with the MTHFR-dependent step as the critical rate-limiting bottleneck), Quatrefolic® is immediately bioavailable. It has been demonstrated to have greater stability, solubility, and bioavailability over calcium salt forms of 5-MTHF. This makes it the preferred form for individuals with MTHFR C677T or A1298C variants, which reduce the enzyme’s efficiency by 30–70%.*

MecobalActive™ (Methylcobalamin, Vitamin B12) MecobalActive™ delivers B12 as methylcobalamin — the neurologically active coenzyme form of B12 that is directly utilized for myelin sheath maintenance, red blood cell formation, and DNA synthesis. Standard supplements use cyanocobalamin, which must first be converted to methylcobalamin in the liver — a conversion that becomes progressively less efficient with age and under conditions of hepatic stress.*

Benfotiamine (Fat-Soluble Thiamine) Benfotiamine is a fat-soluble derivative of thiamine (B1) with significantly greater bioavailability and tissue penetration than standard water-soluble thiamine HCl. Its fat-soluble nature allows it to cross cell membranes more readily, making it more physiologically active at supporting healthy carbohydrate metabolism, mitochondrial function, and nerve tissue health.*

Pyridoxal-5-Phosphate (P5P, Active B6) P5P is the active coenzyme form of vitamin B6, involved in over 100 enzymatic reactions including neurotransmitter synthesis (serotonin, dopamine, GABA), amino acid metabolism, and hormone regulation. Standard pyridoxine HCl must be phosphorylated in the liver to become P5P — a step that may be compromised under conditions of liver stress or certain genetic variants.*

Riboflavin-5-Phosphate (Active B2) The active coenzyme form of riboflavin, required for FAD and FMN enzyme activity and for the proper function of the mitochondrial electron transport chain. Active B2 is also a required cofactor for the MTHFR enzyme itself — making riboflavin-5-phosphate directly relevant to methylation cycle efficiency.*

The Methylation Connection

The methylation cycle is one of the most fundamental biochemical pathways in human physiology. It underlies DNA synthesis and repair, epigenetic gene regulation, detoxification of hormones and environmental compounds, neurotransmitter synthesis and breakdown, immune cell production, and the conversion of homocysteine to methionine. When methylation is suboptimal — often due to B vitamin insufficiency, MTHFR variants, or elevated physiological demand — the downstream effects can manifest across virtually every body system.*

Unique Verve’s B-Complex Does Not Contain

Wheat, gluten, yeast, soy protein, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

How To Take Unique Verve B-Complex

Take one capsule once or twice daily, or as directed by your healthcare practitioner.

Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner.

Quality, Purity, Potency Guaranteed

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)

Made and Packaged in the USA

Unique Verve B-Complex Supplement Facts & Ingredients

Serving Size: 1 Capsule
Servings Per Container: 90

** Daily Value not established.
Thiamine (as thiamine HCI) 20mg 1667%
Riboflavin (as riboflavin 5’-phosphate sodium) 20 mg 1538%
Niacin (130 mg as niacinamide and 10 mg as niacin) 140 mg 875%
Vitamin B6 (as pyridoxal 5’-phosphate)
20 mg 1176%
Folate (as Quatrefolic® (6S)-5-methyltetrahydrofolic acid, glucosamine salt) 400 mcg DFE 100%
Vitamin B12 (as MecobalActiveTM methylcobalamin) 400 mcg 16,667% Biotin 400 mcg 1333%
Pantothenic Acid (as d-calcium pantothenate) 150 mg 3000%
Choline (as choline dihydrogen citrate) 30 mg 5%
Benfotiamine 20 mg **

Other Ingredients

HPMC (capsule), stearic acid, magnesium stearate, and silica.

Legal disclaimer

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. You should consult with a healthcare provider before beginning any dietary supplements.