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NutriCleanse GHI

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NutriCleanse GHI is a comprehensive, monk-fruit-extract-sweetened, low-allergy–potential dietary supplement designed to support gastrointestinal (GI) function and balanced detoxification. It features Vegan Protein Blend, Unique Verve’s proprietary amino acid and pea/rice protein blend; Aminogen®, to facilitate protein absorption; phytonutrients; mineral amino acid chelates; and activated B vitamins, including Quatrefolic® and methylcobalamin.

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Description

In conjunction with a modified elimination diet, NutriCleanse GHI addresses GI and hepatic function as well as eicosanoid balance and cytokine metabolism. This formula is suitable for vegans.

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

Key Benefits & Actions:

  • Supports Natural Detoxification Mechanisms
  • Supports Gastrointestinal Health
  • Supports a Balanced Cytokine Profile
  • Lactose-Free Vegan Protein

Does Not Contain:

Wheat, gluten, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or artificial preservatives.

Directions:

Blend, shake, or briskly stir 2 level scoops (53 g) into 10-12 ounces chilled, pure water (or mix amount for desired thickness) and consume once daily, or use as directed by your healthcare practitioner.

Consult your healthcare practitioner prior to use. Individuals taking medication should discuss potential interactions with their healthcare practitioner.

All Unique Verve Formulas Meet or Exceed cGMP Quality Standards and are manufactured and stored in the temperature and humidity regulated facility in USA.

cGMP = Current Good Manufacturing Practice certification means that every aspect of all Unique Verve manufacturing process has been examined, including laboratory/testing methods (for stability, potency and product formulation)

Made and Packaged in the USA

Supplement Facts:

Serving Size: 2 Scoops (about 53 g) Servings Per Container: About 14

Ingredients:

Percent Daily Values (DV) are based on a 2,000 calorie diet.
** %Daily Value (DV) not established.

Calories 210
Total Fat 8 g 10%*
Saturated Fat 2 g 10%*
Total Carbohydrate 10 g 4%*
Dietary Fiber 4 g 14%
Protein 26 g
Vitamin A (as natural beta-carotene) 750 mcg 83%
Vitamin C (as sodium ascorbate) 250 mg 278%
Thiamin (as thiamine HCl) 15 mg 1250%
Riboflavin (as riboflavin 5′-phosphate sodium) 5 mg 385%
Niacin (as niacinamide and niacin) 40 mg 250%
Vitamin B6 (as pyridoxal 5’-phosphate) 5 mg 294%
Folate (as Quatrefolic® (6S)-5-methyltetrahydrofolic acid,glucosamine
salt) 200 mcg DFE 50%
Vitamin B12 (as methylcobalamin) 50 mcg 2083%
Biotin 150 mcg 500%
Pantothenic Acid (as d-calcium pantothenate) 35 mg 700%
Choline (as choline bitartrate) 100 mg 18%
Calcium (as DimaCal® di-calcium malate and ingredients with naturally
occurring calcium) 225 mg 17%
Iron (naturally occurring) 5 mg 28%
Iodine (as potassium iodide) 60 mcg 40%
Magnesium (as Albion® di-magnesium malate) 140 mg 33%
Zinc (as TRAACS® zinc bisglycinate chelate) 10 mg 91%
Selenium (as Albion® selenium glycinate complex) 100 mcg 182%
Manganese (as TRAACS® manganese bisglycinate chelate) 2 mg 87%
Chromium (as TRAACS® chromium nicotinate glycinate chelate) 60 mcg 171%
Molybdenum (as TRAACS® molybdenum glycinate chelate) 35 mcg 78%
Sodium (from ingredients with naturally occurring sodium, sodium sulfate
anhydrous, and sodium ascorbate) 560 mg 24%
Potassium (from tripotassium citrate and ingredients with naturally occurring potassium) 455 mg 10%
Stabilized Flaxseed 5.6 g **Typical Alpha-Linolenic Acid Content 1.28 g
**

Typical Linoleic Acid Content 392 mg **
Pomegranate Extract (Punica granatum)(hull)(40% ellagic acid) 400 mg **
Betaine Anhydrous (trimethylglycine) 250 mg **
Lemon Bioflavonoid Complex (Citrus × limon)(fruit peel)(25% bioflavonoids) 250 mg **
Quercetin (as quercetin dihydrate from Dimorphandra mollis)(pod)250 mg
**
Preventium® (potassium d-glucarate) 250 mg **
Rutin (from Sophora japonica)(bud) 200 mg **

BCM-95® Turmeric Extract (Curcuma longa)(rhizome)(95% total curcuminoids complex, including curcumin, curcuminoids, and volatile oils)(86% curcuminoids)(65% curcumin) 200 mg **

N-Acetyl-L-Cysteine 150 mg **
Ginger (Zingiber officinale)(rhizome)150 mg **
Methylsulfonylmethane (MSM) 120 mg **
Sodium Sulfate Anhydrous 100 mg ** Watercress (Nasturtium officinale)(aerial parts) 100 mg **
Green Tea Aqueous Extract (Camellia sinensis)(leaf)(80% polyphenols, 60% catechins, 30% EGCG, 6% caffeine) 82 mg **

Other Ingredients:

Vegan Protein Blend (Unique Verve’s proprietary blend of pea protein isolate, taurine, glycine, rice protein concentrate, and L-glutamine), sunfloweroil, natural flavors (no MSG), medium-chain triglyceride oil, cellulose gum, xanthan gum, AMINOGEN® fungal proteases, monk fruit extract, guar gum, and silica.

AMINOGEN® is a registered trademark of Innophos Nutrition, Inc.
AMINOGEN® is protected under U.S. patent 5,387,422.

® Quatrefolic® is a registered trademark of Gnosis S.p.A. Produced under
US Patent 7,947,662.
Preventium® is a registered trademark of Applied Food Sciences, LLC. (US
patents 4,845,123, 5,364,644, 5,561,160).®

LEGAL DISCLAIMER:

*Disclaimer: Statements made, or products sold through this website have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health concerns.

Discussion

NutriCleanse GHI

is now sweetened with a natural, high-potency sweetener extracted from monk fruit. This generally recognized as safe (GRAS) monk-fruit extract offers a high-quality sweetness and flavor without the bitter after taste associated with some natural sweeteners.

Protein Metabolism

Vegan Protein Blend is Unique Verve’s proprietary blend of pea protein isolate and rice protein concentrate, L-glutamine, glycine, and taurine. Generation of glutathione and sulfation cofactors—vital for phase II conjugation—requires an array of amino acids. The combination of pea protein and rice protein, containing a complement of amino acids, achieves an amino acid score of 100%. Glutamine, a conditionally essential and versatile amino acid with two nitrogen moieties, is crucial to nitrogen metabolism and helps maintain healthy liver tissue and function.The amino acid glycine is needed for bile synthesis, phase II detoxification, and glutathione production. Taurine, a derivative of the sulfur-containing amino acid cysteine, is also important for synthesis of bile salts and helps stabilize cell membranes.

Gastrointestinal Support

Ginger root, included to support healthy digestion such as the release of bile from the gallbladder, acts at several sites to moderate PGE(2) production and support the normal response to inflammation. Fiber (from inulin and flax seeds) supports production of short-chain fatty acids as well as a healthy intestinal flora. MeadowPure, an organic flaxseed complex, possesses excellent oxidative stability, supports antioxidant activity, and provides lignins, soluble fiber, and omega-3 and omega-6 essential fatty acids. Glutamine plays a key role in healthy intestinal cell proliferation and gut barrier integrity, immune function, and normal tissue healing.

Detoxification Support

Ellagic acid (from pomegranate extract) prevents over-induction of CYP1A enzymes, works at the gene level to induce synthesis of glutathione-S-transferases and other phase II activities, binds directly to toxins, and protects DNA and hepatocytes. Watercress is a rich source of beta-phenylethyl isothiocyanate (PEITC)—a versatile compound found to inhibit phase I enzymes and induce the phase II enzymes associated with biotransformation and excretion of toxins. Watercress has been found to contain even stronger phase II inducers known as 7-methylsulfinyheptyl and 8-methylsulfinyloctyl isothiocyanates as well. Green tea catechins not only support antioxidant activity but also appear to act as modulators of phase I and phase II detoxification. Choline is present to support lipid metabolism in the liver and can be converted to betaine, a methyl donor.

The active, bioavailable form of B vitamins (pyridoxal-5’-phosphate (B6), 5-methyltetrahydrofolate (folate), methylcobalamin (B12)) and glycine all support amino acid conjugation and are vital for the detoxification of xenobiotics and xenoestrogens. 5-methyltetrahydrofolate (5-MTHF), methylcobalamin, betaine, and methylsulfonylmethane(MSM) are present to support methylation and detoxification. 5-MTHF supports healthy folate nutrition, especially in individuals with variations in folate metabolism. In NutriCleanse GHI, 5-MTHF is provided as Quatrefolic® for enhanced stability, solubility, and bioavailability.

Preventium®, a patented form of potassium hydrogen d-glucarate, supports glucuronidation. Sulfation is supported by MSM and sodium sulfate. Acetylation is supported by d-calcium pantothenate, pyridoxal-5’-phosphate, and magnesium. Several minerals in NutriCleanse GHI are provided as Albion® mineral chelates and TRAACS® mineral amino acid chelates for enhanced gastrointestinal absorption and bioavailability.

Antioxidant Support and Cytokine Balance

Bioflavonoids, quercetin, rutin, and curcumin support antioxidant activity, counter free radicals, and support healthy eicosanoid and cytokine metabolism. Curcumin has a long history of use for its support of a normal, healthy response to inflammation. N-acetyl-cysteine (NAC) stimulates glutathione synthesis, enhances glutathione-S-transferase activity, and promotes detoxification. Selenium glycinate provides support for glutathione metabolism and antioxidant protection.

REFERENCES

  1. Glutamine nutrition and requirements: https://pubmed.ncbi.nlm.nih.gov/2119461/
  2. Is glutamine a conditionally essential amino acid?:https://pubmed.ncbi.nlm.nih.gov/2080048/
  3. The effect of extracts from ginger rhizome on inflammatory mediator production: https://pubmed.ncbi.nlm.nih.gov/16709450/
  4. Health effects with consumption of the flax lignan secoisolariciresinoldiglucoside: https://pubmed.ncbi.nlm.nih.gov/20003621/
  5. Structure-function relationships of the dietary anticarcinogen ellagic acid. Carcinogenesis: https://pubmed.ncbi.nlm.nih.gov/8625448/
  6. Hepatoprotective activity of picroliv, curcumin and ellagic acid compared to silymarin on paracetamol induced liver toxicity in mice: https://pubmed.ncbi.nlm.nih.gov/19656205/
  7. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis: https://pubmed.ncbi.nlm.nih.gov/11062158/
  8. Modulation of detoxification enzymes by watercress: in vitro and in vivo investigations in human peripheral blood cells: https://pubmed.ncbi.nlm.nih.gov/19636603/
  9. Dietary green tea extract increases phase 2 enzyme activities in protecting against myocardial ischemia-reperfusion: https://pubmed.ncbi.nlm.nih.gov/20116658/
  10. Linus Pauling Institute: http://lpi.oregonstate.edu/infocenter/othernuts/choline/
  11. http://www.quatrefolic.com/
  12. http://www.albionminerals.com/
  13. Dietary curcumin modulates transcriptional regulators of phase I and phase II enzymes in benzo[a]pyrene-treated mice: mechanism of its anti-initiating action. Carcinogenesis: https://pubmed.ncbi.nlm.nih.gov/18321868/
  14. Quercetin prevents oxidative stress in cirrhotic rats: https://pubmed.ncbi.nlm.nih.gov/17431769/
  15. Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research: https://pubmed.ncbi.nlm.nih.gov/19594223/
  16. Clinical applications of N-acetylcysteine: https://pubmed.ncbi.nlm.nih.gov/9577247/

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